7PYC

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 2-Aminopyridine

Summary for 7PYC

• Entry DOI: 10.2210/pdb7pyc/pdb
• Descriptor: Cholinephosphate cytidylyltransferase, 2-AMINOPYRIDINE, Guanidinium, ... (4 entities in total)
• Functional Keywords: plasmodium falciparum cct inhibitors fragments, structural protein
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 1
• Total formula weight: 20965.32

Authors

Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (deposition date: 2021-10-09, release date: 2022-10-12, Last modification date: 2024-01-31)

• Primary citation: Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R.; Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.36 Å)