7PX3

Structure of U5 snRNP assembly and recycling factor TSSC4 in complex with BRR2 and Jab1 domain of PRPF8

7PX3 の概要

• エントリーDOI: 10.2210/pdb7px3/pdb
• EMDBエントリー: 13690
• 分子名称: U5 small nuclear ribonucleoprotein 200 kDa helicase, Pre-mRNA-processing-splicing factor 8, Protein TSSC4 (3 entities in total)
• 機能のキーワード: spliceosomal biogenesis, splicing
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 264166.35

構造登録者

Bergfort, A.,Kuropka, B.,Ilik, I.A.,Freund, C.,Aktas, T.,Hilal, T.,Weber, G.,Wahl, M.C. (登録日: 2021-10-07, 公開日: 2022-01-26, 最終更新日: 2024-07-17)

• 主引用文献: Bergfort, A.,Hilal, T.,Kuropka, B.,Ilik, I.A.,Weber, G.,Aktas, T.,Freund, C.,Wahl, M.C.; The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.; Nucleic Acids Res., 50:2938-2958, 2022; PubMed: 35188580; DOI: 10.1093/nar/gkac087

実験手法

ELECTRON MICROSCOPY (3.05 Å)