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7PX2

Conotoxin Mu8.1 from Conus mucronatus

Summary for 7PX2
Entry DOI10.2210/pdb7px2/pdb
DescriptorConotoxin Mu8.1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total)
Functional Keywordsconotoxin, toxin
Biological sourceConus mucronatus
Total number of polymer chains6
Total formula weight62651.26
Authors
Mueller, E.,Hackney, C.,Ellgaard, L.,Morth, J.P. (deposition date: 2021-10-07, release date: 2022-11-16, Last modification date: 2024-01-31)
Primary citationHackney, C.M.,Florez Salcedo, P.,Mueller, E.,Koch, T.L.,Kjelgaard, L.D.,Watkins, M.,Zachariassen, L.,Tuelund, P.S.,McArthur, J.R.,Adams, D.J.,Kristensen, A.S.,Olivera, B.,Finol-Urdaneta, R.K.,Safavi-Hemami, H.,Morth, J.P.,Ellgaard, L.
A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3.
Plos Biol., 21:e3002217-e3002217, 2023
Cited by
PubMed: 37535677
DOI: 10.1371/journal.pbio.3002217
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.12 Å)
Structure validation

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