7PUX
Structure of p97 N-D1(L198W) in complex with Fragment TROLL2
Summary for 7PUX
Entry DOI | 10.2210/pdb7pux/pdb |
Descriptor | Transitional endoplasmic reticulum ATPase, ADENOSINE-5'-DIPHOSPHATE, FORMIC ACID, ... (7 entities in total) |
Functional Keywords | hydrolase, p97, vcp, fragment screening |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 53897.66 |
Authors | Bothe, S.,Schindelin, H. (deposition date: 2021-10-01, release date: 2022-12-14, Last modification date: 2024-01-31) |
Primary citation | Bothe, S.,Hanzelmann, P.,Bohler, S.,Kehrein, J.,Zehe, M.,Wiedemann, C.,Hellmich, U.A.,Brenk, R.,Schindelin, H.,Sotriffer, C. Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97 Commun Chem, 5:169-, 2022 Cited by DOI: 10.1038/s42004-022-00782-5PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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