7PT4

Actinobacterial 2-hydroxyacyl-CoA lyase (AcHACL) structure in complex with a covalently bound reaction intermediate as well as products formyl-CoA and acetone

7PT4 の概要

• エントリーDOI: 10.2210/pdb7pt4/pdb
• 分子名称: 2-hydroxyacyl-CoA lyase, THIAMINE DIPHOSPHATE, SULFATE ION, ... (8 entities in total)
• 機能のキーワード: thdp, coa, lyase
• 由来する生物種: Actinomycetospora chiangmaiensis DSM 45062
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 135146.52

構造登録者

Zahn, M.,Rohwerder, T. (登録日: 2021-09-25, 公開日: 2022-02-02, 最終更新日: 2024-01-31)

• 主引用文献: Zahn, M.,Konig, G.,Pham, H.V.C.,Seroka, B.,Lazny, R.,Yang, G.,Ouerfelli, O.,Lotowski, Z.,Rohwerder, T.; Mechanistic details of the actinobacterial lyase-catalyzed degradation reaction of 2-hydroxyisobutyryl-CoA.; J.Biol.Chem., 298:101522-101522, 2022; PubMed: 34952003; DOI: 10.1016/j.jbc.2021.101522

実験手法

X-RAY DIFFRACTION (1.64 Å)