7PRZ

Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with beta-22 Fabs

Summary for 7PRZ

• Entry DOI: 10.2210/pdb7prz/pdb
• Related: 7PRY
• Descriptor: Beta-22 Fab heavy chain, Spike protein S1, Beta-22 Fab light chain, ... (6 entities in total)
• Functional Keywords: sars-cov-2 alpha variant, beta variant, gamma variant, delta variant, b.1.1.7, b.1.351, p.1, b.1.617.2, antibody, receptor-binding-domain, spike, neutralisation, viral protein/immune system, viral protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 74688.72

Authors

Zhou, D.,Ren, J.,Stuart, D.I. (deposition date: 2021-09-22, release date: 2021-12-15, Last modification date: 2024-01-31)

• Primary citation: Liu, C.,Zhou, D.,Nutalai, R.,Duyvesteyn, H.M.E.,Tuekprakhon, A.,Ginn, H.M.,Dejnirattisai, W.,Supasa, P.,Mentzer, A.J.,Wang, B.,Case, J.B.,Zhao, Y.,Skelly, D.T.,Chen, R.E.,Johnson, S.A.,Ritter, T.G.,Mason, C.,Malik, T.,Temperton, N.,Paterson, N.G.,Williams, M.A.,Hall, D.R.,Clare, D.K.,Howe, A.,Goulder, P.J.R.,Fry, E.E.,Diamond, M.S.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R.; The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.; Cell Host Microbe, 30:53-, 2022; PubMed: 34921776; DOI: 10.1016/j.chom.2021.11.013

Experimental method

X-RAY DIFFRACTION (3.2 Å)