Summary for 7PLF
Entry DOI | 10.2210/pdb7plf/pdb |
Descriptor | Carbonic anhydrase 1, ZINC ION, 4-azanyl-6-[1,2,2-tris(chloranyl)ethenyl]benzene-1,3-disulfonamide, ... (4 entities in total) |
Functional Keywords | carbonic anhydrase i, clorsulon, inhibitor, sulfonamide, metalloenzyme, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 58704.50 |
Authors | Angeli, A.,Ferraroni, M. (deposition date: 2021-08-31, release date: 2022-09-07, Last modification date: 2024-02-07) |
Primary citation | Ferraroni, M.,Angeli, A.,Carradori, S.,Supuran, C.T. Inhibition of Schistosoma mansoni carbonic anhydrase by the antiparasitic drug clorsulon: X-ray crystallographic and in vitro studies. Acta Crystallogr D Struct Biol, 78:321-327, 2022 Cited by PubMed: 35234146DOI: 10.1107/S2059798322000079 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.461 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)