7PKI

Crystal structure of human ACE2 bound to the spike receptor-binding domain from a cave bat sarbecovirus closely related to SARS-CoV-2.

Summary for 7PKI

Entry DOI	10.2210/pdb7pki/pdb
Descriptor	Processed angiotensin-converting enzyme 2, GLYCEROL, BANAL 236 coronavirus spike receptor-binding domain, ... (11 entities in total)
Functional Keywords	coronavirus, receptor binding domain, human ace2., viral protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	94118.40
Authors	Baquero, E.,Rey, F.A. (deposition date: 2021-08-25, release date: 2022-01-19, Last modification date: 2024-02-07)
Primary citation	Temmam, S.,Vongphayloth, K.,Baquero, E.,Munier, S.,Bonomi, M.,Regnault, B.,Douangboubpha, B.,Karami, Y.,Chretien, D.,Sanamxay, D.,Xayaphet, V.,Paphaphanh, P.,Lacoste, V.,Somlor, S.,Lakeomany, K.,Phommavanh, N.,Perot, P.,Dehan, O.,Amara, F.,Donati, F.,Bigot, T.,Nilges, M.,Rey, F.A.,van der Werf, S.,Brey, P.T.,Eloit, M. Bat coronaviruses related to SARS-CoV-2 and infectious for human cells. Nature, 604:330-336, 2022 Cited by PubMed: 35172323 DOI: 10.1038/s41586-022-04532-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.94234133444 Å)

Structure validation