7P35
Structure of the SARS-CoV-2 3CL protease in complex with rupintrivir
This is a non-PDB format compatible entry.
Summary for 7P35
Entry DOI | 10.2210/pdb7p35/pdb |
Related | 7ZQV 7ZQW |
Descriptor | 3C-like proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER (3 entities in total) |
Functional Keywords | protease, inhibitor, sars-cov-2, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) |
Total number of polymer chains | 2 |
Total formula weight | 68852.45 |
Authors | Fabrega-Ferrer, M.,Perez-Saavedra, J.,Herrera-Morande, A.,Coll, M. (deposition date: 2021-07-07, release date: 2021-07-21, Last modification date: 2024-05-01) |
Primary citation | Fabrega-Ferrer, M.,Herrera-Morande, A.,Muriel-Goni, S.,Perez-Saavedra, J.,Bueno, P.,Castro, V.,Garaigorta, U.,Gastaminza, P.,Coll, M. Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404. Antiviral Res., 208:105458-105458, 2022 Cited by PubMed: 36336176DOI: 10.1016/j.antiviral.2022.105458 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.256 Å) |
Structure validation
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