7P35
Structure of the SARS-CoV-2 3CL protease in complex with rupintrivir
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA, BBB | 3C-like proteinase | polymer | 306 | 33825.5 | 2 | UniProt (A0A7L9RWV7) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | Growth factor-like peptide,Guanine-N7 methyltransferase,Helicase,Host translation inhibitor nsp1,Leader protein,NendoU,Non-structural protein 10,Non-structural protein 2,Non-structural protein 3,Non-structural protein 4,Non-structural protein 6,Non-structural protein 7,Non-structural protein 8,Non-structural protein 9,ORF1ab polyprotein,Papain-like proteinase,RNA-directed RNA polymerase,Replicase polyprotein 1ab,Uridylate-specific endoribonuclease,p65 homolog |
2 | AAA, BBB | 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | non-polymer | 600.7 | 2 | Chemie (AG7) | |||
3 | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 67651.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1201.4 | |
All* | Total formula weight | 68852.4 |