7P06
Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in outward-facing conformation with ADP-orthovanadate/ATP
Summary for 7P06
Entry DOI | 10.2210/pdb7p06/pdb |
EMDB information | 13145 |
Descriptor | Pleiotropic ABC efflux transporter of multiple drugs, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | abc transporter, antibiotic resistance, membrane protein, fungal infection, transport protein |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Total number of polymer chains | 1 |
Total formula weight | 171692.89 |
Authors | Szewczak-Harris, A.,Wagner, M.,Du, D.,Schmitt, L.,Luisi, B.F. (deposition date: 2021-06-29, release date: 2021-11-10) |
Primary citation | Harris, A.,Wagner, M.,Du, D.,Raschka, S.,Nentwig, L.M.,Gohlke, H.,Smits, S.H.J.,Luisi, B.F.,Schmitt, L. Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5. Nat Commun, 12:5254-5254, 2021 Cited by PubMed: 34489436DOI: 10.1038/s41467-021-25574-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.77 Å) |
Structure validation
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