7P06

Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in outward-facing conformation with ADP-orthovanadate/ATP

7P06 の概要

• エントリーDOI: 10.2210/pdb7p06/pdb
• EMDBエントリー: 13145
• 分子名称: Pleiotropic ABC efflux transporter of multiple drugs, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: abc transporter, antibiotic resistance, membrane protein, fungal infection, transport protein
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 171692.89

構造登録者

Szewczak-Harris, A.,Wagner, M.,Du, D.,Schmitt, L.,Luisi, B.F. (登録日: 2021-06-29, 公開日: 2021-11-10)

• 主引用文献: Harris, A.,Wagner, M.,Du, D.,Raschka, S.,Nentwig, L.M.,Gohlke, H.,Smits, S.H.J.,Luisi, B.F.,Schmitt, L.; Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5.; Nat Commun, 12:5254-5254, 2021; PubMed: 34489436; DOI: 10.1038/s41467-021-25574-8

実験手法

ELECTRON MICROSCOPY (3.77 Å)