7OTP
DNA-PKcs in complex with ATPgammaS-Mg
Summary for 7OTP
| Entry DOI | 10.2210/pdb7otp/pdb |
| EMDB information | 13064 |
| Descriptor | DNA-dependent protein kinase catalytic subunit,DNA-PKcs, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION (3 entities in total) |
| Functional Keywords | complex, inhibitor, dna repair, dna binding protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 1 |
| Total formula weight | 471947.26 |
| Authors | Liang, S.,Thomas, S.E.,Blundell, T.L. (deposition date: 2021-06-10, release date: 2022-01-12, Last modification date: 2022-02-09) |
| Primary citation | Liang, S.,Thomas, S.E.,Chaplin, A.K.,Hardwick, S.W.,Chirgadze, D.Y.,Blundell, T.L. Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs. Nature, 601:643-648, 2022 Cited by PubMed: 34987222DOI: 10.1038/s41586-021-04274-9 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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