7OSY
Human Prolyl-tRNA Synthetase in Complex with L-proline
Summary for 7OSY
Entry DOI | 10.2210/pdb7osy/pdb |
Related | 7OSZ 7OT0 7OT1 7OT2 7OT3 |
Descriptor | Bifunctional glutamate/proline--tRNA ligase, PROLINE, ZINC ION, ... (5 entities in total) |
Functional Keywords | beta barrel, trna synthetase, protein-ligand complex, ligase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 117061.55 |
Authors | Pang, L.,Zitko, J.,Strelkov, S.V.,Weeks, S.D. (deposition date: 2021-06-09, release date: 2021-07-28, Last modification date: 2024-01-31) |
Primary citation | Pang, L.,Weeks, S.D.,Juhas, M.,Strelkov, S.V.,Zitko, J.,Van Aerschot, A. Towards Novel 3-Aminopyrazinamide-Based Prolyl-tRNA Synthetase Inhibitors: In Silico Modelling, Thermal Shift Assay and Structural Studies. Int J Mol Sci, 22:-, 2021 Cited by PubMed: 34360555DOI: 10.3390/ijms22157793 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.23 Å) |
Structure validation
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