7OP7

Bacteroides thetaiotaomicron mannosidase GH2 with beta-manno-configured N-alkyl cyclophellitol aziridine

Summary for 7OP7

• Entry DOI: 10.2210/pdb7op7/pdb
• Descriptor: Beta-mannosidase, 1,2-ETHANEDIOL, (1R,2S,3R,4S,5R,6R)-5-(8-azidooctylamino)-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, ... (6 entities in total)
• Functional Keywords: mannosidase, cyclophellitol aziridine, hydrolase
• Biological source: Bacteroides thetaiotaomicron VPI-5482
• Total number of polymer chains: 2
• Total formula weight: 200657.91

Authors

McGregor, N.G.S.,Beenakker, T.J.M.,Kuo, C.,Wong, C.,Offen, W.A.,Armstrong, Z.,Codee, J.D.C.,Aerts, J.M.F.G.,Florea, B.I.,Overkleeft, H.S.,Davies, G.J. (deposition date: 2021-05-29, release date: 2022-02-02, Last modification date: 2024-01-31)

• Primary citation: McGregor, N.G.S.,Kuo, C.L.,Beenakker, T.J.M.,Wong, C.S.,Offen, W.A.,Armstrong, Z.,Florea, B.I.,Codee, J.D.C.,Overkleeft, H.S.,Aerts, J.M.F.G.,Davies, G.J.; Synthesis of broad-specificity activity-based probes for exo -beta-mannosidases.; Org.Biomol.Chem., 20:877-886, 2022; PubMed: 35015006; DOI: 10.1039/d1ob02287c

Experimental method

X-RAY DIFFRACTION (1.85 Å)