7OCB
Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B
Summary for 7OCB
Entry DOI | 10.2210/pdb7ocb/pdb |
Descriptor | Spindlin-1, 7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-2N-[2-(dimethylamino)ethyl]-6-methoxy-4N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine, PHOSPHATE ION, ... (8 entities in total) |
Functional Keywords | chromatin, epigenetics, methyl reader, inhibitor, cell cycle |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 26549.36 |
Authors | Johansson, C.,Krojer, T.,Park, K.,Xiong, Y.,Jin, J.,Oppermann, U. (deposition date: 2021-04-26, release date: 2022-05-04, Last modification date: 2024-01-31) |
Primary citation | Johansson, C.,Krojer, T.,Park, K.,Xiong, Y.,Jin, J.,Oppermann, U. Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
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