7OBW

Crystal structure of the ferric enterobactin receptor (PfeA) from Pseudomonas aeruginosa in complex with TCV-L6

This is a non-PDB format compatible entry.

Summary for 7OBW

• Entry DOI: 10.2210/pdb7obw/pdb
• Descriptor: Ferric enterobactin receptor, [4-[[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-[2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]ethanoylamino]propanoyl]amino]propanoyl]amino]methyl]-1,2,3-triazol-1-yl]methyl 4-[4-[(5~{S})-5-(acetamidomethyl)-2-oxidanylidene-1,3-oxazolidin-3-yl]-2-fluoranyl-phenyl]piperazine-1-carboxylate, FE (III) ION, ... (4 entities in total)
• Functional Keywords: siderophore transporter, membrane protein
• Biological source: Pseudomonas aeruginosa PAO1
• Total number of polymer chains: 1
• Total formula weight: 80852.89

Authors

Moynie, L.,Naismith, J.H. (deposition date: 2021-04-23, release date: 2021-08-04, Last modification date: 2024-01-31)

• Primary citation: Moynie, L.,Hoegy, F.,Milenkovic, S.,Munier, M.,Paulen, A.,Gasser, V.,Faucon, A.L.,Zill, N.,Naismith, J.H.,Ceccarelli, M.,Schalk, I.J.,Mislin, G.L.A.; Hijacking of the Enterobactin Pathway by a Synthetic Catechol Vector Designed for Oxazolidinone Antibiotic Delivery in Pseudomonas aeruginosa .; Acs Infect Dis., 8:1894-1904, 2022; PubMed: 35881068; DOI: 10.1021/acsinfecdis.2c00202

Experimental method

X-RAY DIFFRACTION (2.66 Å)