7O4G

Human phosphomannomutase 2 (PMM2) wild-type soaked with the activator glucose 1,6-bisphosphate

Summary for 7O4G

Entry DOI	10.2210/pdb7o4g/pdb
Descriptor	Phosphomannomutase 2, GLYCEROL, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	glycobiology, congenital disorders of glycosylation, phosphotransferase, phosphomutase, isomerase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	57135.54
Authors	Ramon-Maiques, S.,Briso-Montiano, A.,Del Cano-Ochoa, F.,Vilas, A.,Perez, B.,Rubio, V. (deposition date: 2021-04-06, release date: 2022-02-02, Last modification date: 2024-01-31)
Primary citation	Briso-Montiano, A.,Del Cano-Ochoa, F.,Vilas, A.,Velazquez-Campoy, A.,Rubio, V.,Perez, B.,Ramon-Maiques, S. Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45:318-333, 2022 Cited by PubMed: 34859900 DOI: 10.1002/jimd.12461 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.66 Å)

Structure validation