7O45
Crystal structure of ADD domain of the human DNMT3B methyltransferase
Summary for 7O45
Entry DOI | 10.2210/pdb7o45/pdb |
Descriptor | Isoform 6 of DNA (cytosine-5)-methyltransferase 3B, ZINC ION, BROMIDE ION, ... (4 entities in total) |
Functional Keywords | methyltransferase 3b, dna methylation, dnmt3b, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 67251.37 |
Authors | Boyko, K.M.,Nikolaeva, A.Y.,Bonchuk, A.N.,Georgiev, P.G.,Popov, V.O. (deposition date: 2021-04-05, release date: 2022-04-13, Last modification date: 2024-01-31) |
Primary citation | Boyko, K.,Arkova, O.,Nikolaeva, A.,Popov, V.O.,Georgiev, P.,Bonchuk, A. Structure of the DNMT3B ADD domain suggests the absence of a DNMT3A-like autoinhibitory mechanism. Biochem.Biophys.Res.Commun., 619:124-129, 2022 Cited by PubMed: 35760008DOI: 10.1016/j.bbrc.2022.06.036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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