7O27

Crystal structure of the human METTL3-METTL14 complex bound to Compound 17 (ADO_AE_005)

7O27 の概要

• エントリーDOI: 10.2210/pdb7o27/pdb
• 分子名称: N6-adenosine-methyltransferase catalytic subunit, N6-adenosine-methyltransferase non-catalytic subunit, 4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]phenyl]-9-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,4,9-triazaspiro[5.5]undecan-2-one, ... (5 entities in total)
• 機能のキーワード: mettl3, inhibitor, complex, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 62312.01

構造登録者

Bedi, R.K.,Dolbois, A.,Caflisch, A. (登録日: 2021-03-30, 公開日: 2021-09-15, 最終更新日: 2024-01-31)

• 主引用文献: Bedi, R.K.,Dolbois, A.,Caflisch, A.; Crystal structure of the human METTL3-METTL14 complex bound to Compound 17 (ADO_AE_005); To Be Published,

実験手法

X-RAY DIFFRACTION (2.4 Å)