7O0C

Human phosphomannomutase 2 (PMM2) wild-type in apo state

Summary for 7O0C

• Entry DOI: 10.2210/pdb7o0c/pdb
• Related: 2AMY 2Q4R
• Descriptor: Phosphomannomutase 2, MAGNESIUM ION, SODIUM ION, ... (5 entities in total)
• Functional Keywords: glycobiology, congenital disorders of glycosylation, phosphotransferase, phosphomutase, isomerase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 56704.33

Authors

Ramon-Maiques, S.,Briso-Montiano, A.,Del Cano-Ochoa, F.,Vilas, A.,Perez, B.,Rubio, V. (deposition date: 2021-03-26, release date: 2022-02-02, Last modification date: 2024-01-31)

• Primary citation: Briso-Montiano, A.,Del Cano-Ochoa, F.,Vilas, A.,Velazquez-Campoy, A.,Rubio, V.,Perez, B.,Ramon-Maiques, S.; Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures.; J Inherit Metab Dis, 45:318-333, 2022; PubMed: 34859900; DOI: 10.1002/jimd.12461

Experimental method

X-RAY DIFFRACTION (2.8 Å)