7NZT

Crystal structure of chimeric carbonic anhydrase VA with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide

Summary for 7NZT

• Entry DOI: 10.2210/pdb7nzt/pdb
• Related: 7NZR 7NZS
• Descriptor: Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: drug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 30043.32

Authors

Smirnov, A.,Manakova, E.,Grazulis, S. (deposition date: 2021-03-24, release date: 2022-04-13, Last modification date: 2024-01-31)

• Primary citation: Smirnov, A.; Crystal structure of chimeric carbonic anhydrase VA; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.35 Å)