7NVY
RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position
Summary for 7NVY
Entry DOI | 10.2210/pdb7nvy/pdb |
EMDB information | 12617 |
Descriptor | TFIIH basal transcription factor complex helicase XPD subunit, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase II subunit RPB3, ... (35 entities in total) |
Functional Keywords | initiation, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 32 |
Total formula weight | 1296262.07 |
Authors | Aibara, S.,Schilbach, S.,Cramer, P. (deposition date: 2021-03-16, release date: 2021-05-05, Last modification date: 2024-07-10) |
Primary citation | Aibara, S.,Schilbach, S.,Cramer, P. Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594:124-128, 2021 Cited by PubMed: 33902107DOI: 10.1038/s41586-021-03554-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (7.3 Å) |
Structure validation
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