7NTB

Crystal structure of human carbonic anhydrase with a benzophenone-derivative

Summary for 7NTB

Entry DOI	10.2210/pdb7ntb/pdb
Descriptor	Carbonic anhydrase 2, ZINC ION, ~{N}-[[4-(phenylcarbonyl)phenyl]methyl]-4-sulfamoyl-benzamide, ... (5 entities in total)
Functional Keywords	protein-inhibitor adduct, lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	29939.42
Authors	Di Fiore, A.,De Simone, G. (deposition date: 2021-03-09, release date: 2022-03-16, Last modification date: 2024-01-31)
Primary citation	Pagnozzi, D.,Pala, N.,Biosa, G.,Dallocchio, R.,Dessi, A.,Singh, P.K.,Rogolino, D.,Di Fiore, A.,De Simone, G.,Supuran, C.T.,Sechi, M. Interaction Studies between Carbonic Anhydrase and a Sulfonamide Inhibitor by Experimental and Theoretical Approaches Acs Med.Chem.Lett., 13:271-277, 2022 Cited by DOI: 10.1021/acsmedchemlett.1c00644 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation