7NPM
X-ray structure of the adduct formed upon reaction of oxaliplatin with human angiogenin
This is a non-PDB format compatible entry.
Summary for 7NPM
Entry DOI | 10.2210/pdb7npm/pdb |
Descriptor | Angiogenin, PLATINUM (II) ION, D(-)-TARTARIC ACID, ... (4 entities in total) |
Functional Keywords | oxaliplatin, cancer, angiogenesis, protein metallation, angiogenin, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 14679.11 |
Authors | Ferraro, G.,Merlino, A. (deposition date: 2021-02-27, release date: 2022-03-23, Last modification date: 2024-02-07) |
Primary citation | Marzo, T.,Ferraro, G.,Cucci, L.M.,Pratesi, A.,Hansson, O.,Satriano, C.,Merlino, A.,La Mendola, D. Oxaliplatin inhibits angiogenin proliferative and cell migration effects in prostate cancer cells. J.Inorg.Biochem., 226:111657-111657, 2022 Cited by PubMed: 34784565DOI: 10.1016/j.jinorgbio.2021.111657 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
Download full validation report