7NNS

Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound Momelotinib

7NNS の概要

• エントリーDOI: 10.2210/pdb7nns/pdb
• 分子名称: Activin receptor type I, 1,2-ETHANEDIOL, Momelotinib, ... (5 entities in total)
• 機能のキーワード: kinase, bmp, inhibitor, signalling, signaling protein
• 由来する生物種: Homo sapiens
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35996.94

構造登録者

Williams, E.,Chen, Z.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N. (登録日: 2021-02-25, 公開日: 2021-04-07, 最終更新日: 2024-01-31)

• 主引用文献: Williams, E.,Chen, Z.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N.; Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound Momelotinib; To Be Published,

実験手法

X-RAY DIFFRACTION (2.14 Å)