7NNC

Crystal structure of Mycobacterium tuberculosis ArgD with prosthetic group pyridoxal-5'-phosphate and 6-Methoxyquinoline-3-carboxylic acid

Summary for 7NNC

Entry DOI	10.2210/pdb7nnc/pdb
Descriptor	Acetylornithine aminotransferase, NITRATE ION, 6-methoxyquinoline-3-carboxylic acid, ... (4 entities in total)
Functional Keywords	argd, n-acetylornithine aminotrasferase, acoat, transferase
Biological source	Mycobacterium tuberculosis H37Rv
Total number of polymer chains	4
Total formula weight	165627.34
Authors	Gupta, P.,Mendes, V.,Blundell, T.L. (deposition date: 2021-02-24, release date: 2021-06-30, Last modification date: 2024-01-31)
Primary citation	Gupta, P.,Thomas, S.E.,Zaidan, S.A.,Pasillas, M.A.,Cory-Wright, J.,Sebastian-Perez, V.,Burgess, A.,Cattermole, E.,Meghir, C.,Abell, C.,Coyne, A.G.,Jacobs, W.R.,Blundell, T.L.,Tiwari, S.,Mendes, V. A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19:3491-3506, 2021 Cited by DOI: 10.1016/j.csbj.2021.06.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation