7NLP

Crystal structure of Mycobacterium tuberculosis ArgB in complex with L-canavanine

Summary for 7NLP

• Entry DOI: 10.2210/pdb7nlp/pdb
• Descriptor: Acetylglutamate kinase, L-CANAVANINE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: argb acetylglutamate kinase, transferase
• Biological source: Mycobacterium tuberculosis H37Rv
• Total number of polymer chains: 1
• Total formula weight: 31485.20

Authors

Mendes, V.,Thomas, S.E.,Cory-Wright, J.,Blundell, T.L. (deposition date: 2021-02-22, release date: 2021-06-30, Last modification date: 2024-01-31)

• Primary citation: Gupta, P.,Thomas, S.E.,Zaidan, S.A.,Pasillas, M.A.,Cory-Wright, J.,Sebastian-Perez, V.,Burgess, A.,Cattermole, E.,Meghir, C.,Abell, C.,Coyne, A.G.,Jacobs, W.R.,Blundell, T.L.,Tiwari, S.,Mendes, V.; A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis; Comput Struct Biotechnol J, 19:3491-3506, 2021; DOI: 10.1016/j.csbj.2021.06.006

Experimental method

X-RAY DIFFRACTION (2.213 Å)