7NL1

Crystal structure of cystathionine gamma-lyase from Toxoplasma gondii

Summary for 7NL1

• Entry DOI: 10.2210/pdb7nl1/pdb
• Descriptor: Cystathione gamma lyase, putative, PYRIDOXAL-5'-PHOSPHATE (3 entities in total)
• Functional Keywords: transsulfuration pathway, cysteine, hydrogen sulfide, plp dependent, cytosolic protein
• Biological source: Toxoplasma gondii (strain ATCC 50611 / Me49)
• Total number of polymer chains: 8
• Total formula weight: 369829.30

Authors

Fernandez-Rodriguez, C.,Conter, C.,Recio, I.,Astegno, A.,Martinez-Cruz, L.A. (deposition date: 2021-02-22, release date: 2022-03-02, Last modification date: 2024-02-07)

• Primary citation: Fernandez-Rodriguez, C.,Conter, C.,Oyenarte, I.,Favretto, F.,Quintana, I.,Martinez-Chantar, M.L.,Astegno, A.,Martinez-Cruz, L.A.; Structural basis of the inhibition of cystathionine gamma-lyase from Toxoplasma gondii by propargylglycine and cysteine.; Protein Sci., 32:e4619-e4619, 2023; PubMed: 36883335; DOI: 10.1002/pro.4619

Experimental method

X-RAY DIFFRACTION (2.331 Å)