Summary for 7NFV
Entry DOI | 10.2210/pdb7nfv/pdb |
Descriptor | Papain-like protease nsp3, ZINC ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | papain-like protease sars-cov-2 hydrolase zinc binding protein, hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 1 |
Total formula weight | 35994.88 |
Authors | Srinivasan, V.,Gunther, S.,Reinke, P.,Werner, N.,Falke, S.,Brognaro, H.,Ullah, N.,Andaleeb, H.,Perbandt, M.,Alves Franca, B.,Schwinzer, M.,Wang, M.,Sprenger, J.,Lieske, J.,Ginn, H.,Lane, T.J.,Yefanov, O.,Gelisio, L.,Koua, F.,Saouane, S.,Tolstikova, A.,Groessler, M.,Fleckenstein, H.,Ewert, W.,Trost, F.,Lorenzen, K.,Schubert, R.,Han, H.,Schmidt, C.,Brings, L.,Ehrt, C.,Rarey, M.,Galchenkova, M.,Gevorkov, Y.,Li, C.,Perk, A.,Awel, S.,Hinrichs, W.,Meents, A.,Betzel, C. (deposition date: 2021-02-07, release date: 2021-02-24, Last modification date: 2024-01-31) |
Primary citation | Srinivasan, V.,Brognaro, H.,Prabhu, P.R.,de Souza, E.E.,Gunther, S.,Reinke, P.Y.A.,Lane, T.J.,Ginn, H.,Han, H.,Ewert, W.,Sprenger, J.,Koua, F.H.M.,Falke, S.,Werner, N.,Andaleeb, H.,Ullah, N.,Franca, B.A.,Wang, M.,Barra, A.L.C.,Perbandt, M.,Schwinzer, M.,Schmidt, C.,Brings, L.,Lorenzen, K.,Schubert, R.,Machado, R.R.G.,Candido, E.D.,Oliveira, D.B.L.,Durigon, E.L.,Niebling, S.,Garcia, A.S.,Yefanov, O.,Lieske, J.,Gelisio, L.,Domaracky, M.,Middendorf, P.,Groessler, M.,Trost, F.,Galchenkova, M.,Mashhour, A.R.,Saouane, S.,Hakanpaa, J.,Wolf, M.,Alai, M.G.,Turk, D.,Pearson, A.R.,Chapman, H.N.,Hinrichs, W.,Wrenger, C.,Meents, A.,Betzel, C. Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease. Commun Biol, 5:805-805, 2022 Cited by PubMed: 35953531DOI: 10.1038/s42003-022-03737-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
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