7NBK

Solution structure of DNA duplex containing a 2'-deoxy-2'2'-difluorodeoxycytidine (gemcitabine) modification

Summary for 7NBK

• Entry DOI: 10.2210/pdb7nbk/pdb
• Related: 7NBL
• NMR Information: BMRB: 34594
• Descriptor: DNA (5'-D(*CP*GP*TP*AP*(FFC)P*G)-3') (1 entity in total)
• Functional Keywords: fluorine modification, modified dna, gemcitabine, dna
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 3690.40

Authors

Cabrero, C.,Martin-Pintado, N.,Mazzini, S.,Gargallo, R.,Eritja, R.,Avino, A.,Gonzalez, C. (deposition date: 2021-01-27, release date: 2021-04-07)

• Primary citation: Cabrero, C.,Martin-Pintado, N.,Mazzini, S.,Gargallo, R.,Eritja, R.,Avino, A.,Gonzalez, C.; Structural Effects of Incorporation of 2 -Deoxy-2 2 -difluorodeoxycytidine (Gemcitabine) in A- and B-form Duplexes.; Chemistry, 2021; PubMed: 33772916; DOI: 10.1002/chem.202100503

Experimental method

SOLUTION NMR