7NB9
E. coli NfsA with nitrofurantoin
Summary for 7NB9
Entry DOI | 10.2210/pdb7nb9/pdb |
Descriptor | Oxygen-insensitive NADPH nitroreductase, FLAVIN MONONUCLEOTIDE, 1-[(~{E})-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione, ... (5 entities in total) |
Functional Keywords | complex with antibiotic substrate, flavoprotein, nitroreductase, oxidoreductase |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 1 |
Total formula weight | 27605.30 |
Authors | Day, M.D.,Jarrom, D.,Grainger, A.I.,Parr, R.J.,Hyde, E.I.,White, S.A. (deposition date: 2021-01-25, release date: 2021-07-21, Last modification date: 2024-01-31) |
Primary citation | Day, M.A.,Jarrom, D.,Christofferson, A.J.,Graziano, A.E.,Anderson, J.L.R.,Searle, P.F.,Hyde, E.I.,White, S.A. The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN. Biochem.J., 478:2601-2617, 2021 Cited by PubMed: 34142705DOI: 10.1042/BCJ20210160 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.09 Å) |
Structure validation
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