7N5C

6218 TCR in complex with H2Db PA with an engineered TCR-pMHC disulfide bond

7N5C の概要

• エントリーDOI: 10.2210/pdb7n5c/pdb
• 分子名称: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, peptide from Polymerase acidic protein, ... (7 entities in total)
• 機能のキーワード: major histocompatibility complex, mhc, mouse, influenza a, polymerase acidic protein, h2db, t cell receptor, pa224-233, disulfide bond, cysteine, immune system
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 95324.26

構造登録者

Szeto, C.,Gras, S. (登録日: 2021-06-05, 公開日: 2022-07-20, 最終更新日: 2023-10-18)

• 主引用文献: Szeto, C.,Zareie, P.,Wirasinha, R.C.,Zhang, J.B.,Nguyen, A.T.,Riboldi-Tunnicliffe, A.,La Gruta, N.L.,Gras, S.,Daley, S.R.; Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.; Nat Commun, 13:4951-4951, 2022; PubMed: 35999236; DOI: 10.1038/s41467-022-32692-4

実験手法

X-RAY DIFFRACTION (1.87 Å)