7N4E
Escherichia coli sigma 70-dependent paused transcription elongation complex
Summary for 7N4E
Entry DOI | 10.2210/pdb7n4e/pdb |
EMDB information | 24148 |
Descriptor | DNA (61-MER), MAGNESIUM ION, DNA-directed RNA polymerase subunit alpha, ... (10 entities in total) |
Functional Keywords | elongation, pausing, sigma 70, transcription complex, dna scrunching, transferase-dna-rna complex, transferase/dna/rna |
Biological source | Escherichia coli More |
Total number of polymer chains | 9 |
Total formula weight | 501403.34 |
Authors | Molodtsov, V.,Su, M.,Ebright, R.H. (deposition date: 2021-06-04, release date: 2022-06-15, Last modification date: 2024-05-29) |
Primary citation | Pukhrambam, C.,Molodtsov, V.,Kooshkbaghi, M.,Tareen, A.,Vu, H.,Skalenko, K.S.,Su, M.,Yin, Z.,Winkelman, J.T.,Kinney, J.B.,Ebright, R.H.,Nickels, B.E. Structural and mechanistic basis of sigma-dependent transcriptional pausing. Proc.Natl.Acad.Sci.USA, 119:e2201301119-e2201301119, 2022 Cited by PubMed: 35653571DOI: 10.1073/pnas.2201301119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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