7MXY

Cryo-EM structure of PfFNT-inhibitor complex

Summary for 7MXY

• Entry DOI: 10.2210/pdb7mxy/pdb
• EMDB information: 24076
• Descriptor: Formate-nitrite transporter, (Z)-4,4,5,5,5-pentakis(fluoranyl)-1-(4-methoxy-2-oxidanyl-phenyl)-3-oxidanyl-pent-2-en-1-one (3 entities in total)
• Functional Keywords: pffnt, lactate transporter, pffnt-mmv007839 complex, transport protein-inhibitor complex, transport protein/inhibitor
• Biological source: Plasmodium falciparum (isolate 3D7)
• Total number of polymer chains: 5
• Total formula weight: 174022.35

Authors

Yu, E.W.,Su, C.,Lyu, M. (deposition date: 2021-05-19, release date: 2021-12-08, Last modification date: 2024-05-29)

• Primary citation: Lyu, M.,Su, C.,Kazura, J.W.,Yu, E.W.; Structural basis of transport and inhibition of the Plasmodium falciparum transporter PfFNT; EMBO Rep, 22:e51628-, 2021; PubMed: 33471955; DOI: 10.15252/embr.202051628

Experimental method

ELECTRON MICROSCOPY (2.18 Å)