7MXF

CD1c with antigen analogue 2

Summary for 7MXF

• Entry DOI: 10.2210/pdb7mxf/pdb
• Descriptor: T-cell surface glycoprotein CD1c, T-cell surface glycoprotein CD1b chimeric protein, Beta-2-microglobulin, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: lipid, cd1c, antigen-presenting, tuberculosis, lipid binding protein, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 46355.34

Authors

Cao, T.P.,Shahine, A.,Rossjohn, J. (deposition date: 2021-05-19, release date: 2021-11-17, Last modification date: 2023-10-18)

• Primary citation: Reijneveld, J.F.,Marino, L.,Cao, T.P.,Cheng, T.Y.,Dam, D.,Shahine, A.,Witte, M.D.,Filippov, D.V.,Suliman, S.,van der Marel, G.A.,Moody, D.B.,Minnaard, A.J.,Rossjohn, J.,Codee, J.D.C.,Van Rhijn, I.; Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells.; J.Biol.Chem., 297:101197-101197, 2021; PubMed: 34536421; DOI: 10.1016/j.jbc.2021.101197

Experimental method

X-RAY DIFFRACTION (2 Å)