7MXE

Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab

7MXE の概要

• エントリーDOI: 10.2210/pdb7mxe/pdb
• EMDBエントリー: 24072
• 分子名称: 8ANC195 G52K5 Fab heavy chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
• 機能のキーワード: viral protein-immune system complex, non-neutralizing, antiviral protein, antiviral protein-viral protein complex, antiviral protein/viral protein
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 14
• 化学式量合計: 440649.06

構造登録者

Abernathy, M.E.,Bjorkman, P.J. (登録日: 2021-05-19, 公開日: 2021-10-27, 最終更新日: 2021-11-03)

• 主引用文献: Abernathy, M.E.,Gristick, H.B.,Vielmetter, J.,Keeffe, J.R.,Gnanapragasam, P.N.P.,Lee, Y.E.,Escolano, A.,Gautam, R.,Seaman, M.S.,Martin, M.A.,Nussenzweig, M.C.,Bjorkman, P.J.; Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope.; Npj Vaccines, 6:126-126, 2021; PubMed: 34697307; DOI: 10.1038/s41541-021-00387-4

実験手法

ELECTRON MICROSCOPY (3.7 Å)