7MSQ

Complex between the Fab arm of AB-3467 and the SARS-CoV-2 receptor binding domain (RBD)

7MSQ の概要

• エントリーDOI: 10.2210/pdb7msq/pdb
• 分子名称: Spike protein S1, AB-3467 Fab Heavy Chain, AB-3467 Fab Light Chain, ... (8 entities in total)
• 機能のキーワード: sars-cov-2 receptor binding domain ab-3467, antiviral protein, viral protein-antiviral protein complex, viral protein/antiviral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 145714.09

構造登録者

Langley, D.B.,Christ, D. (登録日: 2021-05-12, 公開日: 2022-01-19, 最終更新日: 2023-10-18)

• 主引用文献: Burnett, D.L.,Jackson, K.J.L.,Langley, D.B.,Aggrawal, A.,Stella, A.O.,Johansen, M.D.,Balachandran, H.,Lenthall, H.,Rouet, R.,Walker, G.,Saunders, B.M.,Singh, M.,Li, H.,Henry, J.Y.,Jackson, J.,Stewart, A.G.,Witthauer, F.,Spence, M.A.,Hansbro, N.G.,Jackson, C.,Schofield, P.,Milthorpe, C.,Martinello, M.,Schulz, S.R.,Roth, E.,Kelleher, A.,Emery, S.,Britton, W.J.,Rawlinson, W.D.,Karl, R.,Schafer, S.,Winkler, T.H.,Brink, R.,Bull, R.A.,Hansbro, P.M.,Jack, H.M.,Turville, S.,Christ, D.,Goodnow, C.C.; Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.; Immunity, 54:2908-2921.e6, 2021; PubMed: 34788600; DOI: 10.1016/j.immuni.2021.10.019

実験手法

X-RAY DIFFRACTION (2.29 Å)