7MPG

Cryo-EM structure of Prefusion-stabilized RSV F (DS-Cav1) in complex with Fab AM14

Summary for 7MPG

• Entry DOI: 10.2210/pdb7mpg/pdb
• EMDB information: 23933
• Descriptor: Fusion glycoprotein F0,Envelope glycoprotein, AM14 Fab Heavy Chain, AM14 Fab Light Chain, ... (4 entities in total)
• Functional Keywords: antigen, antibody, epitope, vaccine, structural vaccinology, immune system
• Biological source: Human respiratory syncytial virus; More
• Total number of polymer chains: 9
• Total formula weight: 321836.89

Authors

Abeyrathne, P.D.,Malito, E.,Harshbarger, W.D. (deposition date: 2021-05-04, release date: 2021-09-08)

• Primary citation: Harshbarger, W.,Abeyrathne, P.D.,Tian, S.,Huang, Y.,Chandramouli, S.,Bottomley, M.J.,Malito, E.; Improved epitope resolution of the prefusion trimer-specific antibody AM14 bound to the RSV F glycoprotein.; Mabs, 13:1955812-1955812, ; PubMed: 34420474; DOI: 10.1080/19420862.2021.1955812

Experimental method

ELECTRON MICROSCOPY (3.4 Å)