7MKX
Crystal Structure Analysis of human CDK2 and CCNA2 complex
Summary for 7MKX
Entry DOI | 10.2210/pdb7mkx/pdb |
Descriptor | Cyclin-dependent kinase 2, Cyclin-A2, 2-[(5-bromo-2-{4-[(cyanomethyl)sulfamoyl]anilino}pyrimidin-4-yl)amino]-6-fluorobenzamide (3 entities in total) |
Functional Keywords | cyclin dependent kinase, cell cycle, dna damage, atp-binding, small molecule inhibitor, tumor suppression, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 131169.26 |
Authors | Seo, H.-S.,Dhe-Paganon, S. (deposition date: 2021-04-27, release date: 2022-11-09, Last modification date: 2024-10-23) |
Primary citation | Seo, H.-S.,Dhe-Paganon, S. Crystal Structure Analysis of human CDK2 and CCNA2 complex To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.08 Å) |
Structure validation
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