7MKH
Paired helical tau filament extracted from GSS Patient brain tissue | tau filament from Gerstmann Straussler Scheinker disease | PHF Tau
Summary for 7MKH
Entry DOI | 10.2210/pdb7mkh/pdb |
EMDB information | 23894 |
Descriptor | Isoform Tau-F of Microtubule-associated protein tau (1 entity in total) |
Functional Keywords | tau filament, gss, prp-caa, amyloid fibril, alzheimer disease, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 10 |
Total formula weight | 459198.71 |
Authors | Hoq, M.R. (deposition date: 2021-04-23, release date: 2021-07-28, Last modification date: 2024-05-29) |
Primary citation | Hallinan, G.I.,Hoq, M.R.,Ghosh, M.,Vago, F.S.,Fernandez, A.,Garringer, H.J.,Vidal, R.,Jiang, W.,Ghetti, B. Structure of Tau filaments in Prion protein amyloidoses. Acta Neuropathol, 142:227-241, 2021 Cited by PubMed: 34128081DOI: 10.1007/s00401-021-02336-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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