7MK8

Crystal structure of a surface mutant of human fetal-specific CYP3A7 bound to dithiothreitol

Summary for 7MK8

• Entry DOI: 10.2210/pdb7mk8/pdb
• Descriptor: Isoform 2 of Cytochrome P450 3A7, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... (5 entities in total)
• Functional Keywords: cytochrome p450, cyp3a7, surface mutations, dithiothreitol, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 121058.27

Authors

Sevrioukova, I.F. (deposition date: 2021-04-21, release date: 2021-06-02, Last modification date: 2023-10-18)

• Primary citation: Sevrioukova, I.F.; Structural Basis for the Diminished Ligand Binding and Catalytic Ability of Human Fetal-Specific CYP3A7.; Int J Mol Sci, 22:-, 2021; PubMed: 34072457; DOI: 10.3390/ijms22115831

Experimental method

X-RAY DIFFRACTION (2.15 Å)