7MJ9

HLA-A*02:01 bound to Neuroblastoma Derived mutant IGFBPL1 peptide

Summary for 7MJ9

• Entry DOI: 10.2210/pdb7mj9/pdb
• Descriptor: MHC class I antigen, Beta-2-microglobulin, Insulin-like growth factor-binding protein-like 1 altered peptide, ... (4 entities in total)
• Functional Keywords: lymphoma kinase-derived neuroblastoma tumor antigen, human major histocompatibility complex class i, mhc-i, complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 44994.21

Authors

Toor, J.S.,Tripathi, S.M.,Truong, H.V.,Yarmarkovich, M.,Maris, J.M.,Sgourakis, N.G. (deposition date: 2021-04-19, release date: 2021-08-18, Last modification date: 2023-10-18)

• Primary citation: Yarmarkovich, M.,Marshall, Q.F.,Warrington, J.M.,Premaratne, R.,Farrel, A.,Groff, D.,Li, W.,di Marco, M.,Runbeck, E.,Truong, H.,Toor, J.S.,Tripathi, S.,Nguyen, S.,Shen, H.,Noel, T.,Church, N.L.,Weiner, A.,Kendsersky, N.,Martinez, D.,Weisberg, R.,Christie, M.,Eisenlohr, L.,Bosse, K.R.,Dimitrov, D.S.,Stevanovic, S.,Sgourakis, N.G.,Kiefel, B.R.,Maris, J.M.; Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.; Nature, 599:477-484, 2021; PubMed: 34732890; DOI: 10.1038/s41586-021-04061-6

Experimental method

X-RAY DIFFRACTION (1.75 Å)