7MIX
Human N-type voltage-gated calcium channel Cav2.2 in the presence of ziconotide at 3.0 Angstrom resolution
Summary for 7MIX
Entry DOI | 10.2210/pdb7mix/pdb |
EMDB information | 23867 23868 |
Descriptor | Voltage-dependent N-type calcium channel subunit alpha-1B, CHOLESTEROL HEMISUCCINATE, CHOLESTEROL, ... (13 entities in total) |
Functional Keywords | cav2.2, channels, calcium ion-selective, transport protein-toxin complex, drugs, transport protein/toxin |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 453709.62 |
Authors | |
Primary citation | Gao, S.,Yao, X.,Yan, N. Structure of human Ca v 2.2 channel blocked by the painkiller ziconotide. Nature, 596:143-147, 2021 Cited by PubMed: 34234349DOI: 10.1038/s41586-021-03699-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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