7MGE
Structure of C9orf72:SMCR8:WDR41 in complex with ARF1
Summary for 7MGE
Entry DOI | 10.2210/pdb7mge/pdb |
EMDB information | 23827 |
Descriptor | WD repeat-containing protein 41, Guanine nucleotide exchange protein SMCR8, Guanine nucleotide exchange C9orf72, ... (7 entities in total) |
Functional Keywords | complex, autophagy, als, gap, small gtpase, transport protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 230852.46 |
Authors | Su, M.-Y.,Hurley, J.H. (deposition date: 2021-04-12, release date: 2021-06-23, Last modification date: 2024-05-29) |
Primary citation | Su, M.Y.,Fromm, S.A.,Remis, J.,Toso, D.B.,Hurley, J.H. Structural basis for the ARF GAP activity and specificity of the C9orf72 complex. Nat Commun, 12:3786-3786, 2021 Cited by PubMed: 34145292DOI: 10.1038/s41467-021-24081-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.94 Å) |
Structure validation
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