7MGE

Structure of C9orf72:SMCR8:WDR41 in complex with ARF1

Summary for 7MGE

Entry DOI	10.2210/pdb7mge/pdb
EMDB information	23827
Descriptor	WD repeat-containing protein 41, Guanine nucleotide exchange protein SMCR8, Guanine nucleotide exchange C9orf72, ... (7 entities in total)
Functional Keywords	complex, autophagy, als, gap, small gtpase, transport protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	230852.46
Authors	Su, M.-Y.,Hurley, J.H. (deposition date: 2021-04-12, release date: 2021-06-23, Last modification date: 2024-05-29)
Primary citation	Su, M.Y.,Fromm, S.A.,Remis, J.,Toso, D.B.,Hurley, J.H. Structural basis for the ARF GAP activity and specificity of the C9orf72 complex. Nat Commun, 12:3786-3786, 2021 Cited by PubMed: 34145292 DOI: 10.1038/s41467-021-24081-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.94 Å)

Structure validation