7MF4

Crystal structure of Trypanosoma cruzi cytosolic Malic Enzyme

Summary for 7MF4

Entry DOI	10.2210/pdb7mf4/pdb
Related	6W29 6W2N 6W49 6W53 6W56 6W57 6W59
Descriptor	Malic enzyme, CITRIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	cytosol, oxidoreductase
Biological source	Trypanosoma cruzi (strain CL Brener)
Total number of polymer chains	1
Total formula weight	62040.84
Authors	Ranzani, A.T.,Cordeiro, A.T. (deposition date: 2021-04-08, release date: 2021-07-28, Last modification date: 2023-10-18)
Primary citation	Mercaldi, G.F.,Eufrasio, A.G.,Ranzani, A.T.,do Nascimento Faria, J.,Mota, S.G.R.,Fagundes, M.,Bruder, M.,Cordeiro, A.T. Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box. Acs Infect Dis., 7:2455-2471, 2021 Cited by PubMed: 34279922 DOI: 10.1021/acsinfecdis.1c00231 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation