7MEW
E. coli MsbA in complex with G247
Summary for 7MEW
Entry DOI | 10.2210/pdb7mew/pdb |
EMDB information | 23805 |
Descriptor | ATP-dependent lipid A-core flippase, (2E)-3-{1-cyclopropyl-7-[(1S)-1-(3,6-dichloro-2-fluorophenyl)ethoxy]naphthalen-2-yl}prop-2-enoic acid (2 entities in total) |
Functional Keywords | membrane protein |
Biological source | Escherichia coli (strain B / BL21-DE3) |
Total number of polymer chains | 2 |
Total formula weight | 135511.51 |
Authors | Thelot, F.,Liao, M. (deposition date: 2021-04-08, release date: 2021-10-06, Last modification date: 2024-05-29) |
Primary citation | Thelot, F.A.,Zhang, W.,Song, K.,Xu, C.,Huang, J.,Liao, M. Distinct allosteric mechanisms of first-generation MsbA inhibitors. Science, 374:580-585, 2021 Cited by PubMed: 34554829DOI: 10.1126/science.abi9009 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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