7MEV

Human Apex/Ref1 monomer with C138A mutation

Summary for 7MEV

Entry DOI	10.2210/pdb7mev/pdb
Descriptor	DNA-(apurinic or apyrimidinic site) endonuclease, mitochondrial, MAGNESIUM ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	human apex/ref1, dna binding protein, dnase i, metal ion binding
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	31425.08
Authors	Nam, Y.W.,Yang, S. (deposition date: 2021-04-07, release date: 2022-04-13, Last modification date: 2023-10-18)
Primary citation	Nam, Y.W.,Khanjani, E.B.,Fong, S.,Chawla, S.,Rahighi, S.,Ibrahim, N.,Parang, K.,Zhang, M.,Yang, S. The Development of Novel Apurinic/Aprymidinic Endonuclease/Redox-factor 1 Inhibitors for the Treatment of Human Melanoma To Be Published,
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation