7MDL
High-resolution crystal structure of human SepSecS-tRNASec complex
Summary for 7MDL
| Entry DOI | 10.2210/pdb7mdl/pdb |
| Descriptor | O-phosphoseryl-tRNA(Sec) selenium transferase, RNA (90-MER), (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ... (5 entities in total) |
| Functional Keywords | selenocysteine synthesis, protein translation, plp-dependent enzyme, rna binding, transferase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 5 |
| Total formula weight | 262375.13 |
| Authors | Puppala, A.,French, R.L.,Simonovic, M. (deposition date: 2021-04-05, release date: 2022-11-09, Last modification date: 2023-10-25) |
| Primary citation | Puppala, A.K.,Castillo Suchkou, J.,French, R.L.,Kiernan, K.A.,Simonovic, M. Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans. Nucleic Acids Res., 2023 Cited by PubMed: 36929010DOI: 10.1093/nar/gkad182 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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